Unmasking protective mask types to prevent coronavirus and more

You can bitch, moan, or debate about PPP and PPE. Wearing a protective mask and pair of gloves during a horrible disease pandemic is a necessary prophylactic, both courteous and wise. What were once used as options in factories, medical and science offices are now more essential wearables in a world where tiny microbes coexist with us through an invisible masks.

People tend to shy from using prophylactics such as a protective mask. Another form of prophylactic is use of a condom. The global rate of unintended pregnancy was estimated at 44% of all pregnancies between 2010 and 2014, corresponding to approximately 62 unintended pregnancies per 1000 women between the ages of 15–44 years old. One in two sexually active persons will contract an STI by age 25. The Centers for Disease Control and Prevention (CDC) estimates that nearly 20 million new STIs occur every year in this country, half of those among young people aged 15–24. Yet the use of condoms as a prophylactic measure remains constant.

We take our breathing and our respiratory health for granted, but the lung is a vital organ that is vulnerable to airborne infection and injury. Respiratory diseases are leading causes of death and disability in the world. Coronavirus-19 barely comes close to those numbers but ranks high among infectious, contagious diseases. Virus based colds are varied. Flu is a common, common cold. Discovery and use of flu vaccines help make incidence less common. Each year new viruses develop and attack unprotected immune systems. According to CDC, about 400,000 patents were hospitalized with a viral infection, each year, over the past decade. Many of those patients died because of respiratory issues that occured prior to flu.

Wearing a protective mask and gloves, especially in dense populations, may prevent these “colds” from spreading to others. Or prevent their colds spreading to you. Sneezes and coughs spread droplets of microbes and some are infectious. Using a hand or sleeve to cover a sneeze is no sure way of filtering spread to others or to items they carry. Viruses are tiny microbes. They are about 1/3 of 1 micron in size. If you lined them on a ruler, there might be over 100,000 to an inch. A protective mask helps filter viruses from entering nose and mouth. What was optional in the 20th century seems more reasonable in the 21st. Microscopes that discovered tiny microbes (electron microscopes) were more accessible to labs in the 1960’s. Perhaps there’s a lesson we should learn during this pandemic. A protective mask, gloves, and some proportionate social distancing may help humans survive better into the 22nd century. Scientists have only been glimpsing into sub-micron sized particles for the past 50 years and their behaviors.

There are many protective masks. Let’s explore a few. There are basics: homemade cloth face mask, surgical mask {procedure and respirator), N95/N98/N99?N100 respirator.Many are made of paper and are disposable. Some are plastic and N100 is notably metallic. On those masks there are filters (often carbon) that are replaceable.

A surgical/procedure mask is a 3-layer to 5-layers protective sheet, rectangular, with ear loops or head-straps. The are usually common and affordable. Most masks worn during routine medical exams are also found in nail salons. This mask is a loose-fitting disposable mask that protects the wearer’s nose and mouth from contact with droplets, splashes and sprays that may contain germs. A surgical mask also filters out large particles in the air. Surgical masks may protect others by reducing exposure to the saliva and respiratory secretions of the mask wearer. These generally do not have FDA approval for surgical use. They are fine for l;leisure walking, short periods, with social distancing. Protection might be 70 to 90% and are comfortable.

There are fabric masks, usually handmade or fashionable, that function like procedure masks. They tend to protect from colder weather. They are seen as bandanas and scarves as well. Fabrics must be very tightly woven to offer protective mask protection. Mesh won’t do. So inappropriate for summer wear.

Cloth masks may be custom designed and laundered. Cloth masks are cheap and simple to make. Must be tightly stitched as microns get through. CDC offers designs for no-sew that may provide very near to N95 efficiency.

More appropriate for surgery, N95 mask offers more protection than a surgical mask does because it can filter out both large and small particles. The name indicates that the mask is designed to block 95% of very small particles. Like surgical masks, N95 masks are intended to be disposable. However, researchers are testing ways to disinfect N95 masks so they can be reused. These are costlier than procedure masks. Essential oil sprays (tea tree, oregano, eucalyptus) may be antiviral for longer durability but studies are thin. I’dd feel better if surgeon disposes of old masks. For tightest protection, the N95 protective mask manufacturers advise head-straps over ear-loops, clean-shaven instead of beards.

You may have heard of N98, N99, and N100 as a protective mask label. Often respirators with added filters, these may be used by doctors but are more common for use in areas of extreme toxic chemicals. The difference between N95, N99 and N100 masks is simply the filter’s efficiency level. N95 filters 95% of particulates and N99 filters 99% of particulates on the air. The higher the efficiency, the more particulates respirator will filter out. That means microns are virtually filtered.

N100 masks are designed to protect the wearer from inhaling non-oil-based particulates, and according to OSHA standards, they must prevent 99.97 percent of those particulates from getting in when properly worn. The larger, bulky N100 protective mask is designed to block dangerous hazards like lead, cadmium, arsenic and methylenedianiline, commonly referred to as MDA. All the N100 masks usually are NIOSH-approved.

There are also P100 respirator protective mask types. P100 respirators are effective at blocking 99.97 percent of oil-based particulates when properly worn. They can protect wearers from exposure to dust, fumes and hazardous mists. P100 masks are ideal for construction environments, food processing plants, agricultural applications and pharmaceutical manufacturing. They also provide complete protection against non-oil-based particulates, like lead, arsenic and cadmium. P100 respirators are often used during welding, as well.

A protective mask may be created anywhere. Many are manufactured in Asia. The ways to help a consumer find the best protective mask is by regulating standards. You’ve probably heard of OSHA before, the Occupational Health and Safety Administration. NIOSH and OSHA are two sides of the same coin; they are different organizations, but they were both founded with the same act, and they work together to tackle the problem of workplace hazards. Yet, it’s likely that most of the masks used during the Coronavirus-19 pandemic were not manufactured to these standards.

NIOSH is a part of the Centers for Disease Control and Prevention, or CDC. They tend to work more on the research and health side of things. That’s why they’re relevant for masks and respirators; they care about things like air pollution and environmental hazards and safety. So, expect NIOSHA to be recommended by the CDC.

So…many of the disposable procedure and N95 masks may NOT be as efficient as claimed. It’s possible they were designed for cosmetic applications and food preparation instead of medical use. Theoretically, use of a protective mask and a pair of gloves, along with reasonable social distance may help keep some infectious flu microns away.

There are man points and counterpoints about how to live in a world with coronavirus. Habitually wearing a protective mask and pair of gloves when outdoors is your first shield against microbial infections. During a pandemic, epidemic, or “cold” seasons these are prophylactic measures to improve wellness. Yes, you can gamble your health with many things other than microbes. I think wearing a suitable protective mask is a safety net with degrees of assurance.

Coronavirus-19 means there were previous coronaviral sources of the flu. Vaccines contain protection from those. The current microbe is a recmutation. It may not be in every breath you take or in any breath you take or anything you touch but can be encountered, especially among crowds of people. Some, only few have flu-like symptoms and, of those, may be unaware that they are carriers. Using a protective mask and gloves might help reduce the spread of infection.

I think that beyond wearing masks and gloves routinely, social distancing and quarantines may not be necessary. People need liberty to socialize and go places. In cold seasons, I’d advise wearing masks and gloves as a health and fashion ethic. Yet, we see that people don’t use condoms, don’t diet, don’t exercise. Mutual reciprocity in relationships must proximally overcome social barriers. A protective mask needs to become an ethical part of your wardrobe. You are not over-reacting if you use a protective mask within a vetting process. It is mutual protection of the other. Wearing a protective mask and gloves are not punishments. They help prevent disease spread for you and for others.

Respiratory illnesses cost the U.S. economy roughly $40 billion a year — substantially more than other conditions like asthma, heart failure, and emphysema. There are larger numbers when you add non-viral and viral expenses and sick days. Yet group dynamics prove that people don’t follow rules or ethics. You shouldn’t be forced to wear a protective mask if you’re willing to sin against harming others and/or self. Infectious diseases are humanity’s bane. A protective mask and responsible distancing help keep societies and businesses in balance. Let debaters continue to debate with or without masks. Viruses will mutate further. Left futures decide and predict whether these masks may be more necessary than now.

NOMID and COVID multisystem inflammatory disease

Can there be a relationship to the coronavirus-19 (COVID-19) that affects young children? People are talking about it. It’s called NOMID or Neonatal onset multisystem inflammatory disease. Other than both being inflammatory diseases. Are they siblings or distant cousins? They may not be in the same family! What’s the link?

It’s rare. As we immerse ourselves at coronavirus prevention, a disease emerged that affects kids from 2-15. Neonatal-onset multisystem inflammatory disease is a rare genetic periodic fever syndrome which causes uncontrolled inflammation in multiple parts of the body starting in the newborn period. Symptoms include skin rashes, severe arthritis, and chronic meningitis leading to neurologic damage. It’s there since birth but symptoms can show anytime. Is YOUR child safe from multisystem inflammatory disease?

Neonatal onset multisystem inflammatory disease (NOMID) is a disorder that causes persistent inflammation and tissue damage primarily affecting the nervous system, skin, and joints. Recurrent episodes of mild fever may also occur in this disorder. People with NOMID have a skin rash that is usually present from birth.

NOMID is also known as chronic infantile neurologic cutaneous articular (CINCA) syndrome. As a syndrome, it encompasses many neurological diseases and symptoms. While NOMID is a very rare disorder. Only about 100 affected individuals with different ethnic backgrounds have been widely reported. Males and females are equally affected. Yet, within the coronavirus pandemic. NOMID tips the scales to focus on children’s susceptibilities. Some believe there are genetic mutations, much like DDX3, Muscular Dystrophy, and Multiple Sclerosis…among many.

While there are some standard therapies and some under investigation, NOMID
has no cures, much like other diseases from genetic mutations.

NOMID is an American term for CINCA. Statistics of possible CINCA prevalence has been done elsewhere. The exact prevalence of chronic infantile neurological, cutaneous, and articular (CINCA) syndrome is unknown, it is estimated that the whole spectrum of CAPS has a prevalence of 1/360,000 in France, CINCA being the less common form. In the Eurofever registry, collecting information on over 250 patients with NLRP3 mutation, about 25% of the patients present the most severe CINCA phenotype.

Symptoms noted, may confuse parents and pediatricians:

Chronic aseptic meningitis

Progressive profound sensorineural hearing loss in >70%

Increased intracranial pressure

Papilledema – Papilledema is a serious medical condition where the optic nerve at the back of the eye becomes swollen. Symptoms can include visual disturbances, headaches, and nausea.

Headache

Ventriculomegaly – Ventriculomegaly, also known as hydrocephalus, is a condition in which the CSF-filled structures within the brain become larger than normal. As a result, the large ventricles can inhibit the proper development of the brain.

Cerebral atrophy

Seizures

Significant developmental delay

Where 3 or 4 symptoms are chronically present, genetic testing would be required. Advice is to see a pediatric neurologist.

Bringing NOMID/CINCA into the spotlight is that some therapies used seem to also work on COVID-19 patients. This is dissimilar as COVID-19 is viral and NOMID/CINCA is genetic. Whether this loose relationship is better for NOMID patients or COVID patients is like grasping at straws.

Parenting is difficult. Comparing NOMID to COVID-19 leads to overwhelming concerns. Both are actively still seeking treatmets, cures, vaccines. Symptomatically COVID is more respiratory and NOMID relates to irregular brain pressures. I don’t see how one relates to the other.

Coronavirus and food access for mobility challenge

This coronavirus flu pandemic is among the worst flu crises in the past 200 years. Able-body people are forced into quarantine lock downs at home, protective gear, social distancing, and closures of schools and businesses. USA was caught unaware. It was shocking. That includes access to supermarkets. It’s a hysterical situation. Imagine having motor and other disabilities. When those microbes flee and vaccines develop. Most people will gradually normalize. For many people with chronic disability challenges, many challenges that were once somewhat manageable are above and beyond possible.

Quarantines, social distancing, wearing (and finding) protective masks and gloves are large and bitter pills to swallow, even in this digital age. But compared to congestive flu, pneumonia symptoms and death, you deal with it.

When supplies run low, shopping online provides basics but if you have special, dietary needs or seek taste preferences, you may be out of luck. Most people can get to supermarkets and pharmacies that are better supplied and even wait on restrictive lines. People with visual, mobility, emotional, mentally, or otherwise impaired, those challenges are virtually impossible for adaptation.

The global lockdown and social distance is shocking to most people. This Coronavirus pandemic is impacting many lives. For the disabled and for those with chronic mobility challenges, this is even more devastating. Having myotonic muscular dystrophy, lack of accessibility is a permanent condition. Corona virus pandemic attacks the disabled and human civilization with greater than military impunity.

According to statistics gathered by the World Bank, One billion people, or 15% of the world’s population, experience some form of disability, and disability prevalence is higher for developing countries. One-fifth of the estimated global total, or between 110 million and 190 million people, experience significant disabilities. Of course disabilities cover wide ranges and few have been addressed as seriously as coronavirus-19 over the past 4 months.

Confronting dilemmas of coronavirus and disabilities is that disabilities are chronic with no treatments or cures. Acute diseases are the diseases that affects an individual for short span of time. Chronic diseases are the diseases that persist for a long period of time. They develop over a time and does not appear suddenly. For example, Heart disease, kidney disease, neuro-muscular diseases, among others are chronic. Coronavirus is a flu and is acute.

Although acute, and seeming temporary, each year flu can possibly kill many. CDC estimates that influenza was associated with more than 48.8 million illnesses, more than 22.7 million medical visits, 959,000 hospitalizations, and 79,400 deaths during the 2017–2018 influenza season. The coronavirus-19 (SARS-Cov2) of 2020 far exceeds that. Will microbes eventually be the end of human civilization through repeated attacks from infectious microbes? Each year there is a flu season. Some are prevented with researched vaccines. Each year, though, people around the world die from flu diseases. They may be brief but deadly to some. Coronavirus has demonstrated death tolls around the world. And science research is slow in finding weapons.

In the USA, scientific research is usually neglected. Many studies are small, short, and not representative samples of the population. When we debate health care, thorough research usually isn’t factored.

Viruses, bacteria, and fungi are contagious by contact with air, boards, and other materials. Chronic disabilities are likely in genetic or in-utero. Chronic disabilities are not contagious, other than family blood lines.

Both coronavirus and disabilities can shorten lifespan, depending on severity. Living in a quarantine-like environment such as coronavirus restrictions isn’t unique for those with chronic mobile disabilities. Doing things is just more challenging.

People with chronic disabilities need to adapt to the environment. In New York, I don’t go to stores. I shop online or by phone. The store delivers. Under the coronavirus pandemic, shopping is even more challenging because traveling to stores may be extremely difficult. More online stores have established restrictive policies.

People with disabilities aren’t seniors although many seniors have congestive diseases that can confound or amplify coronavirus symptoms. While death might have been accelerated by coronavirus, there may have been others that suppressed the body’s immune system. Generally, proper nutrition is supportive but not medically accepted.

As an acute disease, Coronavirus and lockdowns restrict access to laundries, barbers, hair salons, nail spas and other personal services that people with disabilities make use of. Yes, people on lockdowns are coping with all these services closed.

COVID stress gets worse as lockdowns become longer. People are required to think out-of-the-box to take care of needs they’ve always taken for granted. They must adapt to new and harsher realities as cases and deaths grow higher each day. They must adapt as soldiers without legitimate authority through lockdowns and mandatory social distancing for an undetermined time. Thank heavens for Internet and unemployment!

But this coronavirus pandemic will pass. Human civilizations will normalize. Economies will surge and lives will become better with achievements and joy.

Yet, for people with chronic disabilities who use wheelchairs, walkers, braces and other accessories for different challenges, restrictions will remain with prayers for some ease with access to foods and services. Of course we’ve adapted to problems with maneuvering and travelling in a world full of obstacles. These challenges are permanent (or can get worse). I am motivated to confront my challenges although many days I succumb to failure. Then try to re-adapt. Thinking out-of-the-box and supportive relationships help.

In a world of bullets and bombs, human civilization must appreciate this coronavirus pandemic as evidence that science research against infectious microbes must not be suppressed. The bible talked about breaking swords and making plowshares. Science, responsible lifestyles, and mutual respect may make a better garden grow, amidst climate change and world pollution.

The endgame, as this coronavirus pandemic passes, is that no lessons were learned. Better, more infectious microbes will evolve and attack every few years. Human civilization and our future generations must learn the chronic war against these infectious microbes and furtherance of overall human wellness. Or face extinction like the Aztecs.

The Biblical Book of Isaiah sheds a utopic view of the world. The famous “swords to plowshares” quote (Isaiah 2:4) is but one of its famous proclamations:

And he shall judge among the nations, and shall rebuke many people: and they shall beat their swords into plowshares, and their spears into pruning-hooks: nation shall not lift up sword against nation, neither shall they learn war any more. (Isaiah 2:4).

This goes back nearly 3,000 years. Reference to this or essences appear in the Old Testament, New Testament, and Koran. What is the plowshare we need?

Methodical microbial research will help human civilization span evolution better. Our economy must rely on research for our selves and future generations. This recent pandemic is far more destructive than bullets and bombs.. We must rethink and examine the prophets and create those plowshares to aid global civilizations on an ever-changing planet. Just because you can’t see the attack coming, doesn’t mean it isn’t there. That’s how coronavirus worked this time around.

While climate change and environment are important, generations are best served by research to help prevent pandemics and help the disabled meet challenges with greater dignity and understanding.

Coronavirus dystrophy

Coronavirus Dystrophy? A dystrophy is defined as a disorder in which an organ or tissue of the body wastes away. Dystrophy is globally prevalent, challenging those that fear those tiny microbes and avoid them. Further challenges are ahead for those that test positive. Then there is the likelihood of death. There is no clear cure, treatment, and vaccine.

I have myotonic dystrophy,type 1. Myotonic dystrophy affects at least 1 in 8,000 people worldwide. The prevalence of the two types of myotonic dystrophy varies among different geographic and ethnic populations. In most populations, type 1 appears to be more common than type 2. It is a genetic disease. It also has no clear cure, treatment, or vaccine. Myotonic Dystrophy is among over 150 muscular dystrophies monitored by the global Muscular Dystrophy Association network. It has challenges, disabilities, and deaths.

Greater prevalence and studies were aimed at Duchenne Muscular Dystrophy. At the age of 25, the survival rate was 13.5% in DMD patients born in the 1960s, 31.6% in those born in the 1970s, and 49.2% in patients born in the 1980s. Duchenne muscular dystrophy (DMD) is a muscle disorder but it is one of the most frequent genetic conditions affecting approximately 1 in 3,500 male births worldwide. … The disease is progressive and most affected individuals require a wheelchair by the teenage years.

Coronavirus diseases are types of a dystrophy as it threatens the majorities of people who never gave virus pandemics a second thought. There are many people for whom mobility involves social distancing and constant adaptations every day. More than 18 million people have limited mobility caused by everything from accidents to disease to the aging process. Six million of those 18 million are veterans. One in five elderly people struggle with mobility. The number of veterans with disabilities has increased dramatically by 25 percent since 2001. Many adapt to their world with canes, walkers, prostheses, and wheelchairs.

Coronavirus-19 or SARS-2 viruses are tiny microbes that pass through the air and linger on surfaces. They are germs and we live with germs in and around us every day. Coronavirus-19 is particularly infectious and invisibly travel within environments with wide temperature ranges. Over 400,000 have tested and have caught it. There are about 19,000 deaths attributed, and about 110,000 recoveries globally. About 300,000 are mild and about 110,000 are severe.

The numbers of those testing positive vary. Test availability is low and offered to those who display flu-like symptoms. As more testing is done, total numbers of potential coronavirus-19 cases rise within a distribution of people. Then the question arises whether tests are specifically measuring for coronavirus type viruses or only version 19. Coronavirus is not new to humans. 19 is.

Human coronavirus is a common, enveloped, positive-sense RNA virus, with most people contracting it during their lifetime. Coronaviruses cause mild to moderate upper-respiratory tract illnesses. There are six currently known strains of coronaviruses that infect humans. The most common infection globally is from human coronaviruses 229E, NL63, OC43, and HKU1. The much publicized human coronavirus, SARS-CoV, which causes severe acute respiratory syndrome, or SARS, has a unique pathogenesis because it causes both upper and lower respiratory tract infections and can also cause gastroenteritis. The six human coronaviruses are: alpha coronaviruses 229E and NL63, and beta coronaviruses OC43, HKU1, SARS-CoV (SARS), and MERS-CoV (the coronavirus that causes Middle East Respiratory Syndrome or MERS). Are professionals testing all 6 or only for 1? Test results have changed from taking days to minutes – in just a matter of weeks. Are analyses being compromised? For now,these are the best tests available.

Do pets factor in Sars-Cov spread? Over the last 70 years, scientists have found that coronaviruses can infect mice, rats, dogs, cats, turkeys, horses, pigs, and cattle. Sometimes, these animals can transmit coronaviruses to humans. Ancient plagues were likely results of rodent populations found in the hulls of cargo ships. Naples and Venice were identified as ports that needed to quarantine ships. Rats have been associated with shipping for thousands of years. Roman ships brought the black rat to the British Isles over 1,600 years ago. The brown rat, commonly known as the wharf rat, is found on every continent in the world except Antarctica — much of the spread attributable to being carried on ships and boats. Can hugging your cat or dog give you Sars-Cov? Can breeding animals or poultry contribute to numbers of Coronavirus cases?

A recent Scientific American article considered climate change as a possibility. “As the Earth continues to warm, many scientists expect to see changes in the timing, geography and intensity of disease outbreaks around the world.”

The coronavirus is an uncommonly common influenza or flu that has fever, congestion, coughs, and digestive symptoms. It is one of 6 identifiable types, with many variations and sub-types that are unknown. The World Health Organization estimates that worldwide, annual influenza epidemics result in about 3-5 million cases of severe illness and about 250,000 to 500,000 deaths. In the United States, individual cases of seasonal flu and flu-related deaths in adults are not reportable illnesses; consequently, mortality is estimated by using statistical models.

The US Centers for Disease Control and Prevention (CDC) estimates that flu-associated deaths in the US ranged from about 3000 to 49,000 annually between 1976 and 2006. The CDC notes that the often-cited figure of 36,000 annual flu-related deaths was derived from years when the predominant virus subtype was H3N2, which tends to be more lethal than H1N1. Yes, there are many families of viruses and some have greater and lesser impact. There are flu vaccines available that cover many known viruses.

As with a dystrophy, there are no specific treatments or cures. Unlike dystrophy, a flu tends to be acute rather than chronic. Yet, we know little of coronavirus-19. It, unlike most chronic mobile disabilities, is contagious.

A modeling study in Singapore of Coronavirus-19 (common name) was published 3/24/20 in Lancet, a British Medical Journal:
A new modelling study conducted in a simulated Singapore setting has estimated that a combined approach of physical distancing interventions, comprising quarantine (for infected individuals and their families), school closure, and workplace distancing, is most effective at reducing the number of SARS-CoV-2 cases compared with other intervention scenarios included in the study.

The previous week, the USA NIH/National Institute of Allergy and Infectious Diseases noted that “new research finds that the virus that causes coronavirus disease 2019 (COVID-19) is stable for several hours to days in aerosols and on surfaces. Scientists found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was detectable in aerosols for up to three hours, up to four hours on copper, up to 24 hours on cardboard and up to two to three days on plastic and stainless steel.” It’s contagion possibilities are more enduring than merely sneezes in a public setting. Sneezes and coughs travel as much as 6 feet.

Prior and since this recent pandemic, some scientific studies were done. With small samples and short duration, these study results are rather inconclusive to large populations.

Science experimentation for large groups require time, depth, and retesting. Some are half-baked.

A quasi-experimental design is one that looks a bit like an experimental design but lacks the key ingredient – random assignment. These are “queasy” experiments because they give the experimental purists a queasy feeling. With respect to internal validity, they often appear to be inferior to randomized experiments. But there is something compelling about these designs; taken as a group, they are easily more frequently implemented than their randomized cousins. Queasy is easy.

A clinical study is based on selected populations with random and double-blind secure measures. A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. ClinicalTrials.gov (USA) includes both interventional and observational studies.

ClinicalTrials.gov uses specific strict, ethical guidelines that filter out hunches and opinions. A clinical study is conducted according to a research plan known as the protocol. The protocol is designed to answer specific research questions and safeguard the health of participants. It contains the following information:

The reason for conducting the study
Who may participate in the study (the eligibility criteria)
The number of participants needed
The schedule of tests, procedures, or drugs and their dosages
The length of the study
What information will be gathered about the participants

Conclusions are statistically studied and interpreted. Idea in science is to determine the validity as to whether the original purpose was true or false. As you see, these studies can not be rushed. Many need several clinical trials prior to reaching conclusions. False sponsors and politics can confound results. Personal interests tend to prefer quasi-experiments.

People with dystrophy adapt their lives to a world that doesn’t recognize their special needs to use public and business areas. Many restrict. Years past, these were invalid – not valid individuals. Today. is a bit better. It’s life with distance and restrictions that require adaptations to do activities most take for granted.

Adapting to social distancing and curfews may reduce spread of contagion. We live in a digital age that allows work from home, video-conferencing, social media, investing-banking, and wide access to education and entertainment. Delivery services help businesses bring products and food to customers Coronavirus-19 impact is not yet known. The world is in panic mode. Eventually, a new normal will evolve.

Religious, social, and forums are finding avenues to use online access. Old methods of living are challenged by climate changes, social changes, and new diseases. When online developed, we knew it was wise to use internet security software. As we witness Coronavirus impact, we must study our powers and dystrophy to revise how we coexist with future changes. It’s adapting to new realities, based on our histories.

If one was a gambler, it’s likely that coronavirus 20 may be in our future. Odds are better than an asteroid hitting our planet. At the very least, lessons learned from current coronavirus dystrophy may help us improve coping with subsequent viruses. Rest assured, viruses have existed long before humans. They will evolve ever after.

Viruses will continue to be active and develop to cause new infections. Sars-Cov2 is the root of many fears. We hope that changing lifestyles, social distancing, and temporary quarantines help prevent spread. Continued virology research may produce weapons to allow humans to normalize. After a 2-trillion dollar USA economic package, I hope that the fiscal budgets consider more money to advance virus research to prevent calamities like the SARS-Cov2, coronavirus-19 pandemic. Without it, future generations will develop coronavirus dystrophy.

Coronavirus and the Vegan Diet

Can you get coronavirus from eating a salad or vegan stew? Answer is yes. Wash your produce well and hope.

Coronavirus is the new 4-letter word that spreads like silent snipers through our planet. More people are being tested and, of those results, coronavirus is spreading. Of course, science is grappling with coronavirus by attempting to answer unanswerable questions. Are there false positives from tests? Are tests testing for the right virus? Also sneezes and coughs spread germs. Vegans, picking fruits and vegetables in produce aisles, are especially vulnerable too.

People constantly touch fruits and vegetables. They may also have colds and other seasonal infections. They squeeze items and put noses close to smell freshness, while dropping a few onto the floor.

A preliminary study published this week, used an atomizer to simulate a cough or sneeze spray of coronavirus strain. Discoveries were monitored and shared with Health institutes of University of California, Princeton University, and Center for Disease Control (CDC). The virus could be detected in the air for up to three hours after it was aerosolized with a nebulizer, up to four hours on copper, up to 24 hours on cardboard and up to two to three days on plastic and stainless steel.

Ever think about the surfaces of Apples, Pears, Citrus, Celery, and other produce? Is it possible that hard apples might be stained with coronavirus for days?

In this biome of plant growth, potential edibles are subject to dust, microbes, worms, and larvae of tiny little creatures. Many vegans claim that organic foods are invulnerable due to better care. Actually, that may be untrue. Instead of ordinary pesticides, pesticides from more organic sources are used.

List of Organic Pesticides:

Bacillus Thuringiensis. Bacillus thuringiensis, more commonly referred to as Bt, is a biological pesticide, which means it is a living organism that is in some way lethal to garden or yard pests.

Beauveria Bassiana. Beauveria bassiana is a fungus that grows naturally in soils throughout the world and acts as a parasite on various arthropod species, causing white muscardine disease; it thus belongs to the entomopathogenic fungi.

Kaolin Clay. The use of Kaolin clay in the garden has been found to control insect pests and disease as well as protecting against sunburn or heat stress and may enhance fruit color too.

Neem Oil. Neem oil insecticide kills some pests after they have eaten leaves sprayed with it, while it repels others with its strong smell. Neem oil is used to control many pests, including whitefly, aphids, Japanese beetles, moth larvae, scale, and spider mites.

Pyrethrum. Pyrethrins are pesticides found naturally in some chrysanthemum flowers. They are a mixture of six chemicals that are toxic to insects. Pyrethrins are commonly used to control mosquitoes, fleas, flies, moths, ants, and many other pests. … Whole, crushed flowers are known as pyrethrum powder.

Plant Oils or Biopesticides. Oils such as lemon, orange, and anise give fruits and seeds their characteristic odor and taste. The oils are used as pesticides to repel certain animals and insects, and to kill certain insects. When used as pesticides, these oils do not present any known risks to humans or the environment.

Along with possible Coronavirus from other produce customers and staff, all these organic pesticides may coat your valued foods.

For most part, I see people washing produce for as little as 5 seconds under running water. Is this enough to remove insecticides and viruses like coronavirus? What do you think?

Vegans make it a point to wash produce thoroughly with ritualized practices. Some soak them in baking soda for 2-minutes then rinse thoroughly.

Some soak produce in Apple Cider Vinegar and rinse thoroughly. Some use ultrasonic basins or wands to sterilize the produce. Hopefully viruses like Coronaviruses go down the drain too.

Many people have seasonal colds caused by viruses. They do not respond well to antibiotics. Viruses are another microbial family. Most viral colds go away as weather warms. Viruses don’t survive in heat.

According to a new article in National Geographic, viruses that cause influenza or milder coronaviruses (yes, there are seven in total that affect humans) often subside in warmer months due to a concept called “seasonality,” or a predictable rise and fall depending on the time of year.

This coronavirus strain comes from a new side of the viral family… SARS-CoV-2. There have been reports that infectivity of SARS CoV (SARS coronavirus) was lost after heating at 56°C (132-degF) for 15 minutes but that it was stable for at least 2 days following drying on plastic, in a lab study of 2011 when a SARS flu was present. But this coronavirus (COVID-19) hasn’t been fully examined for high temperature tolerance.

There are 219 virus species that are known to be able to infect humans. The first of these to be discovered was yellow fever virus in 1901, and three to four new species are still being found every year. According to Medicine Plus, They are made of genetic material inside of a protein coating. Viruses cause familiar infectious diseases such as the common cold, flu and warts. They also cause severe illnesses such as HIV/AIDS, smallpox, and Ebola. Different viruses attack certain cells in your body such as your liver, respiratory system, or blood. Some have been associated with cancer growth.

Current coronavirus strain still has more questions than answers. It’s spreading at a moderate but noticeable speed to impact society on many levels. Salads may be a great route to fitness. Vegetarian and vegan lifestyles deem healthy results. But you have to make certain that all produce, organic or conventional, is washed thoroughly. Based on SARS temperature range, I’d advise cooking above that tempoerature.

Navigating yourself and understanding where you are

People with no disabilities and people with disabilities have navigating difficulties. Seems many people have navigating challenges by passivity. Getting safely from Point-A to Point-B may be very challenging. The prompts are coded in Retrosplenial cortex. If you actively and purposefully set landmarks, this part of your brain will get you to A, B, C (and so on) safely.

Getting lost but finding yourself? GPS has been a wonderful navigating tool. It helps drivers find easy ways to get from one location to another. Some people don’t know the correct direction to travel in their local area. Navigating is difficult. For some with cognitive decline, navigating is impossible.

A group of MIT neuroscientists studied navigating and how your brain encodes and decodes landmarks that help you navigate.

Familiar landmarks, using diagnostic testing, asserts that a part of the brain called the retrosplenial cortex (RSC) lights up when you see a landmark and you may decide what you want to do.

Rodents using mazes seem to manage mazes to find cheese reward. Some say it’s part of conditioning. Functional studies of the RSC of rodents consistently point to a role in learning and navigation. These roles are thought to be acted out in concert with the hippocampal formation and the limbic thalamus.

Studies of patients with unilateral retrosplenial damage suggest the RSC has an important contribution to navigation, whereas bilateral retrosplenial damage is often associated with anterograde and varying degrees of retrograde amnesia. The reason? Retrograde amnesia (RA) is a loss of memory-access to events that occurred, or information that was learned in the past.

With no stored landmarks, you’re fundamentally lost though you’ve traveled the area hundreds of times.

Deviations on developing cognitive maps of an area occur with organic damage or as a normal pattern. Everyone has mental maps that they use for navigating; to get around, no matter how “good they are with directions”. Picture your neighborhood, for example. The average person has large mental maps to tell them where towns, states, and countries are positioned and smaller maps to navigate areas like their kitchen. They travel to work, stores, friends, and houses of worship almost automatically. That’s when the RSC knows what it’s doing. Paths are familiar.

There are people that don’t construct mapping for various types of navigating. Those who always travel by car, may have difficulty navigating by walking. The landmarks may be different.

The RSC has been the focus of an increasing amount of research, fueled in part by recent findings that it is among the first cortical regions to exhibit pathology associated with Alzheimer’s disease There is consistent evidence that the RSC suffers very early pathological changes in the progression of mild cognitive impairment and Alzheimer’s disease. Changes in metabolism and physical activity reduction might be contributors.

Long-term memory is thought to rely on the neocortex and is critical for a variety of cognitive processes, including attention, decision making, and new learning. The RSC lies in the midbrain, near the hippocampus, and uses very advanced functions setting spatial memory concepts. Without it, navigating from point A to point B would be impossible. Nor finding your way back to pint A.

Sadly, even the MIT study used rodents as subjects and noted further studies are necessary.

Yet, observation does provide anecdotal evidence that more than a few have cognitive mapping dysfunction, unless there is a known reward.

Cognitive Learning is a type of learning that is active, constructive, and long-lasting. In behavioral geography, a mental map is a person’s point-of-view perception of their area of interaction. They study it to determine subjective qualities from the public such as personal preference and practical uses of geography like driving directions. They use other landmarks as street signs, stores, and other features.

There may be cognitive mapping dysfunction for people with adaptive challenges, as movement decreases. There is no direct evidence.

People without disabilities often use maps or written directions as navigation tools or for remaining oriented. Cognitively-impaired population is very sensitive to issues of abstraction (e.g. icons on maps or signage) and presents the designer with a challenge to tailor navigation information specific to each user and context.

Spatial knowledge is fundamental for the autonomy and the improvement of quality of life for individuals with blindness. Other cues must be learned and mastered to establish maps. Yet, RSC is storing them.

It is unknown whether cognitive function plays a role in the onset of major mobility disability (MMD) and if the effects are independent of physical function. Within neuro- and muscular disorders, purposeful, planned, and structured endeavors undertaken to improve skill or physical fitness level may be helpful. Mapping indoor and outdoor areas for safety require active coding and encoding landmarks for both safety and direction.

Physical activities are those that require energy expenditure and involve bodily movements produced by skeletal muscles. They also involve active thinking, listening to music or not. I prefer navigating without music.

Coronavirus Travel avoiding COVID easily tea tree oil

Living is a contact sport. When a virus seems to spread, human contact is compromised and extra perseverance is taken at hand washing. So Purelle and other disinfectant gels and wipes are out of stock. What about those of us who didn’t prep for this coronavirus epidemic? Think out-of-the box. Tea Tree Oil has both antibacteria, and anti-fungal properties.

According to Medical News Today, Tea tree oil is distilled from the leaves of the Melaleuca alternifolia plant, found in Australia. The oil possesses antibacterial, anti-inflammatory, antiviral, and antifungal properties. A person can treat acne, athlete’s foot, contact dermatitis or head lice using tea tree oil.

Now coronavirus is a result of a virus infection. Many colds are based on viruses. Antibacterial wipes may not be enough. You need to attack viruses. According to Healthline, Tea tree oil has antiviral properties that have proven to be effective against common pathogens. A 2001 study found that a combination of tea tree oil and eucalyptus oil worked effectively against the herpes simplex virus. A 2013 study found that tea tree oil could prevent the spread of influenza.

Researchers, in a 2018 study, have used the antibacterial properties of tea tree oil to create a bioactive coating that keeps bacteria away from medical devices. The findings may help to stave off millions of infections per year. Using special techniques, essential oils can now be turned into a hard, antibacterial surface that protects against infection.

An ideal natural alternative to chemical-based sanitizers, tea tree oil-based sanitizers can be just as effective when it comes to killing several strains of illness-causing bacteria and even more effective with others.

E coli, for instance, was found in some studies to be more effectively broken up and wiped out by tea tree-based agents than when attacked with commercially produced chemical products. Another tick in the tea tree oil box when choosing a hand sanitizer has to come with the fact that it is eminently more environmentally friendly from leaf to litter than the many branded varieties of hand soap.

Essential tea tree oil is not a very expensive essential oil in comparison to other types of oils. You can also use face washes and gels, which contain this oil to soothe your skin on a daily basis.

The funny element is that as hand sanitizers are being bought in response to this possible coronavirus threat, tea tree oil is available. People just don’t think out-of-the-box.

In an article from Medical News Today, Eucalyptus oil shows anti-viral activity as a vapor. Red thyme oil is effective against flu viruses as a liquid phase. Cinnamon leaf oil also shows antiviral activity as a liquid. Tea tree oil is effective against the flu virus within 5 to 10 minutes of exposure, as found in another study.

Admittedly, most studies are small but one study in 2017 tested 3 essential oil mixes and noted that they had antibacteria and anti-fungus properties.

Essential oils have many benefits to protect against coronavirus. Like most beneficial things, there are some consequences. A few essential oils can cause burning when exposed to ultra-violet (UV) lighting. So, before laying out in the sun at the beach or heading to a tanning salon, it is important to ensure that you wait at least 12 hours once a photosensitizing oil has been applied to the skin. Depending on the oil and length of exposure to the sun, skin reactions from certain oils can range from mild discoloration to severe swelling and blistering burns. So read about Tea Tree Oil and become aware that while most people have no side effects, some may develop.

Coronavirus is threatening. Weighing essential oils, that have anti-viral properties, as protection is wise. When trying to act normally with a coronavirus in the environment, something like Tea Tree Oil is a healthy alternative.

May psychedelics help treat mental health and PTSD

While psychedelics epitomized the culture and music of the 1960’s, drug abuse was rampant. As the sun set on the 60s, the US government ramped up its war on drugs and in 1970 President Nixon introduced the Controlled Substances Act, rendering psilocybin, mescaline, LSD and DMT illegal. About 2 weeks ago, John Hopkins School of Medicine received a 17-million dollar grant for study of psychedelics as therapy for PTSD, Depression, Anxiety, and Alzheimer’s Disease.

Included in this study is the party drug of the 1990’s – Ecstcy. Ecstasy works both as a mind-altering drug like LSD and as a stimulant like amphetamine. Chemically, ecstasy is a synthetic drug, officially known as 3-4 methylenedioxymethamphetamine, or “MDMA.” It is chemically similar to methamphetamine, methylenedioxyamphetamine (MDA), and mescaline.

Before prescription drugs, there was alchemy. Alchemy was the medieval forerunner of chemistry, based on the belief that there are four basic elements in nature: air, fire, water and earth. Pantheists used these elements as treatments and cures of sicknesses back then. Consisting of magic potions and secrecy. Now recently marijuana has been associated for relief of pain, nausea, and anorexia. In this rejuvenated plant-based society, chemistry and alchemy find that psychedelics might help treat mental health and PTSD, according to recent research in 2017 and 2018.

Connectedness is considered a key factor of psychological well-being. The authors propose that psychedelic therapy addresses a core factor of mental health – specifically connectedness – and that this is why psychedelics show promise for so many mental health diseases, including depression, addiction and anxiety.

Alchemy used consciousness potions and leaves that induced altered consciousnesses for relaxation, fevers, and undefinable ailments. They were also used for pacts of peace and alliance.

These were psychedelics. For recreation, most psychedelics were prohibited in the 1950’s, as dosages could be fatal and addictive.

According to Yale University research, published January 2020, The results of a field study of more than 1,200 people attending multi-day arts and music festivals in the United States and United Kingdom confirm previous laboratory research indicating that psychedelic substances enhance feelings of social connectedness and improve mental well-being, the authors say.

With veteran soldiers and victims of abusive PTSD, psychedelics may prove to be beneficial. Some cases of PTSD are considered untreatable. But researchers are seeing dramatic results from therapy that uses psychedelic drugs to treat PTSD, depression and addiction. Therapy involving substances like Psilocybin and MDMA, better known as ecstasy, show 80 percent success rates years after treatment.

Yet these trials are done with small and tight clinical trials. According to PubMed, ” Even with an expanding evidence base confirming safety and benefits, political, regulatory, and industry issues impose challenges to the legitimate use of psychedelics.”

Proponents of treatments with psychedelics espouse that these therapeutics also support plant life, in April 2018.

Magic mushrooms are having a therapeutic moment. In North America, at least four organizations, each with unique strategies, are working to expand access to psilocybin for anyone with mental health issues, dying or not. These groups hope to undo decades of psilocybin prohibition by removing criminal penalties for possession or cultivation, or by providing access to psilocybin in a therapist’s offices, or both.

A group of private donors has given $17 million to start the Center for Psychedelic and Consciousness Research at Johns Hopkins Medicine, making it what’s believed to be the first such research center in the U.S., and the largest research center of its kind in the world. In the absence of federal funding for such therapeutic research in people, the new center will rely on the gifts announced today to advance the emerging field of psychedelics for therapies and wellness.

Psychedelics might be an alchemy PAC that is funding research into therapeutic psychedelics. Yet, for those suffering with chronic PTSD, depression, and anxiety disorders, alchemy may be forging a reluctant friendship with the traditional medical community.

In the 1970’s and 1980’s research demonstrated that neurotransmitters were behind the causes of depression, anxiety, and others. The top 3 neurotransmitters are serotonin, nor-epinephrine, and dopamine.

Ecstasy activates these:

Dopamine—produces increased energy/activity and acts in the reward system to reinforce behaviors

Norepinephrine—increases heart rate and blood pressure, which are particularly risky for people with heart and blood vessel problems

Serotonin—affects mood, appetite, sleep, and other functions. It also triggers hormones that affect sexual arousal and trust. The release of large amounts of serotonin likely causes the emotional closeness, elevated mood, and empathy felt by those who use MDMA.

While antidepressants may target any one of these, psychedelics target all. In addition, dosing was not controlled. This often may have led to lethal consequences.

MDMA is a synthetic drug, meaning that it’s made of chemicals. It comes in colorful pills, tablets, or capsules that sometimes have cartoon-like images on them. Sometimes each pill, or batch of pills, can have different combinations of substances in the mix and cause unknown consequences.

Ecstasy is purely lab produced. Psilocybin comes from certain mushrooms. Both are illegal. Ecstasy, also called Molly or MDMA are sometimes found in dietary supplements. RollSafe’s recommended MDMA supplements. Supplements like Alpha Lipoic Acid, ALCAR, Vitamin C, Co-Q10 and some others have been shown to reduce or prevent MDMA-induced neurotoxicity in rodent studies. According to RollSafe, research based information on MDMA (Molly/Ecstasy) dosage: read why you should take less than 120 mg of MDMA per session. None were human studies and this is a shill, marketing ploy, in my opinion.

Of course, water, salt, pepper, are chemicals. Psilocybin is a phytonutrient found in a certain breed of mushrooms. Psilocybin is a hallucinogenic substance people ingest from certain types of mushroom that grow in regions of Europe, South America, Mexico, and the United States. The phtonutrient itself isn’t illegal but body conversion is. After the gut ingests and absorbs psilocybin, the body converts it to psilocyn. The hallucinogenic effects of psilocybin usually occur within 30 minutes of ingestion and last between 4 and 6 hours.

While there are no extensive studies of therapeutic effects within controlled scientific environments, there’s yet no reliability that psychedelics play significant roles in treatment of depression, anxiety, and PTSD. There have been a few smaller studies in recent years that offered hope.

The big flaws are in humans themselves. Exceeding dosages, all these drugs are abused. Also, no side-effects have been clinically shown.

It might be nice if psychedelics played significant roles in treating these common chronic ailments. Finances may be biased and skewed as the are sourced from MAPS, Multidisciplinary Association for Psychedelic Studies.

The Johns Hopkins grant lends a respectable medical institution, one that played an important role in isolating the first neurotransmitters. Solomon Snyder Laboratory at Johns Hopkins, cited evidence that information processing in the brain reflects communication among neurons via neurotransmitters.

Metformin and diabetes scare

Diabetes is a pandemic with prevalence in USA and most of the world. Metformin is one of the oral pills prescribe by doctors as an alternative to injected insulin. Metformin is a treatment for Diabetes 2. In order to get cured, a diet and exercise regimen must be integrated as a routine lifestyle. Sadly, most people continue taking pills, drink soda, eat Oreo, and watch TV. Then they wonder why Metformin dose increases as Diabetes grows worse.

More than 100 million U.S. adults are now living with diabetes or prediabetes, according to a recent report released by the Centers for Disease Control and Prevention (CDC). People with type 1 diabetes don’t produce insulin, and are born with it. People with type 2 diabetes don’t respond to insulin as well as they should and later in the disease often don’t make enough insulin, according to Healthline. There have been higher incidences of Diabetes Type 2. Type 2 diabetes has several causes: genetics and lifestyle are the most important ones. A combination of these factors can cause insulin resistance, when your body doesn’t use insulin as well as it should. You may not feel it. Could be major or minor. A blood test at your primary care physician is the best way to get clues.

So you’ve got the results of your blood test. Basic glucose is in normal range. Your triglycerides are in the normal range. But the Hemoglobin A1C is getting mighty close to the pre-diabetic range. The A1c test evaluates the average amount of glucose in the blood over the last 2 to 3 months by measuring the percentage of glycated hemoglobin in the blood and has been added to blood tests over the past 10 years. Now your doctor recommends starting Metformin on prescription. Metformin is a commonly prescribed drug. Metformin works to lower the amount of sugar in the blood of people with diabetes. It does this by lowering the amount of sugar produced in the liver, and also increasing the sensitivity of muscle cells to insulin. In your blood test, it helps reduce your Hemoglobin A1c score. Does it make you non-diabetic?

There are a few things to consider:

Metformin leads to significant reduction in testosterone levels, sex drive and induction of low testosterone-induced erectile dysfunction. Of course so can diabetes.

Commonly reported side effects of metformin include: lactic acidosis, diarrhea, nausea, nausea and vomiting, vomiting, and flatulence. Other side effects include: asthenia, and decreased vitamin B12 serum concentrate. 77% of metformin users with vitamin B12 deficiency also had peripheral neuropathy, a common form of nerve damage associated with type 2 diabetes. Peripheral neuropathy is a type of nerve damage most often characterized by pain, tingling, and numbness in the hands and feet. Vitamin B-12, or cobalamin, is a nutrient you need for good health. It’s one of eight B vitamins that help the body convert the food you eat into glucose, which gives you energy.

Impaired renal function can lead to the accumulation of metformin, and elevated concentrations of metformin have been associated with lactic acidosis.: Metformin may have an adverse effect on renal function in patients with type 2. Metformin is not considered intrinsically hepatotoxic. In fact, metformin may be beneficial in patients with nonalcoholic fatty liver disease. Damaged liver diseases may not work with metformin.

Metformin has been around since the 1920’s. It is based on natural sources. Metformin was originally developed from natural compounds found in the plant Galega officinalis, known as French lilac or goat’s rue. Metformin was also marketed as Glucophage. Generic metformin and Glucophage are prescription medications for Diabetes Type 2, and are taken orally.

We mention that Diabetes 2 may be linked to poor diets and lack of exercise. Medical News Today notes: Exercise can reduce insulin resistance and improve type 2 diabetes symptoms. However, some research suggests that taking metformin in the short term may reduce the positive effects of exercise on insulin sensitivity. One study showed metformin alone and exercise alone led to 55% and 90% improvements in skeletal muscle insulin sensitivity, respectively. Significantly, however, metformin + exercise led to a smaller improvement at 30%.

Is it better to focus on activity lifestyle changes than resorting to Meformin? Does diet factor in?

Per Healthline, Metformin doesn’t really link with helping weight loss. f you’re losing weight while taking metformin, it may or may not be the result of the medication. Weight loss can result from other factors as well. For example, some health conditions may cause loss of appetite, which can lead to weight loss. These conditions include:
depression
stress
anxiety
chronic obstructive pulmonary disease (COPD)
cancer
AIDS
Parkinson’s disease

Classic signs and symptoms that suggest you’ve moved from prediabetes to type 2 diabetes include:
Increased thirst.
Frequent urination.
Fatigue.
Blurred vision.

The symptoms of diabetes 2 are something to get depressed and anxious about. The early signs and symptoms of type 2 diabetes can include:
Frequent urination.
Increased thirst.
Always feeling hungry.
Feeling very tired.
Blurry vision.
Slow healing of cuts and wounds.
Tingling, numbness, or pain in the hands or feet.
Patches of dark skin.

According to Mayo Clinic, a blood sugar level less than 140 mg/dL (7.8 mmol/L) is considered normal. A blood sugar level from 140 to 199 mg/dL (7.8 to 11.0 mmol/L) is considered prediabetes. This is sometimes referred to as impaired glucose tolerance. If you receive a prediabetes diagnosis, it means you have a higher-than-normal blood sugar level. But, it’s not high enough to be diagnostic for diabetes. If you don’t get treatment for it, prediabetes can lead to type 2 diabetes, heart disease, and stroke.

Now Hemoglobin A1C makes it simpler. An A1C level below 5.7 percent is considered normal. An A1C level between 5.7 and 6.4 percent is considered prediabetes. Above that, you’ve Diabetes 2 to contend with.

Hypoglycemia is another non-diabetic form of pre-diabetes. Hypoglycemia is the condition when your blood glucose (sugar) levels are too low. It happens to people with diabetes when they have a mismatch of medicine, food, and/or exercise. Non-diabetic hypoglycemia, a rare condition, is low blood glucose in people who do not have diabetes.

Hyperglycemia is the technical term for high blood glucose (blood sugar). High blood sugar happens when the body has too little insulin or when the body can’t use insulin properly.

More doctors and endocrine specialists are happy to prescribe Metformin merely from A1C test results but when you observe the different mechanisms of diabetes a glucose tolerance test should be recommended. A glucose tolerance test measures how well your body’s cells are able to absorb glucose (sugar) after you consume a specific amount of sugar. Doctors use fasting blood sugar levels and hemoglobin A1c values to diagnose type 1 and type 2 diabetes as well as prediabetes. These tests may last 1 to 3 hours on average.

According to Healthline, a two-hour, 75-gram oral glucose tolerance test (OGTT) is used to test for diabetes. A healthcare provider will take a fasting lab draw of blood to test your fasting glucose level first. They’ll then ask you to drink 8 ounces of a syrupy glucose solution that contains 75 grams of sugar.

You’ll then wait in the office for two hours. The healthcare provider will draw blood at the one- and two-hour marks.

Blood glucose, or sugar, is sugar that is in your blood (easy enough!). It comes from the food that you eat — foods that contain carbohydrate, such as bread, pasta and fruit are the main contributors to blood glucose. The cells in our bodies need glucose for energy — and we all need energy to move, think, learn and breathe. The brain, which is the command center, uses about half of all the energy from glucose in the body. When we eat food, the pancreas (an organ that sits between the stomach and the spine) goes to work, releasing enzymes that help to break down food and hormones that help the body handle the influx of glucose. One of these hormones is insulin, and it plays a key role in managing glucose levels in the blood.

The lifestyle changes are exercises and reducing carbohydrate consumption throughput the day.

There are supplements that may be good alternatives to Metformin use:

Chromium is an essential trace mineral that helps the hormone insulin to function at its full potential. Nicotinate and picolinate are two forms of chromium. … Additionally, in a direct comparison against chromium nicotinate, the picolinate source was less effective in supporting the action of insulin.

Cinnamon may help lower blood sugar and fight diabetes by imitating the effects of insulin and increasing glucose transport into cells ( 6 ). It can also help lower blood sugar by increasing insulin sensitivity, making insulin more efficient at moving glucose into cells.

Vanadium compounds are potent in controlling elevated blood glucose levels in experimentally induced diabetes. However the toxicity associated with vanadium limits its role as therapeutic agent for diabetic treatment.

Bitter melon is linked to lowering the body’s blood sugar. This is because the bitter melon has properties that act like insulin, which helps bring glucose into the cells for energy.

Of course neither of these supplements haven’t received FDA approval to support or deny their claims. Most evidence is derived from small studies in Europe and Asia.

Sunergetic Blood Sugar Support has all the above and more. It helps me keep my A1C scores within normal range. But this claim is by no means scientific.

Large overdoses of metformin can lead to lactic acidosis as well. Suicide with metformin is rare. Intake of 35 g of metformin has been shown to be lethal. Severe liver problems could lead to a buildup of lactic acid. Lactic acid buildup raises your risk of lactic acidosis. Metformin also raises your risk, so taking it if you have liver problems is dangerous.

Because supplements have little supporting research, no figures were established. Properly dosing supplements requires a good licensed nutritionist. It will help recommend dosage to avoid side effects. Doctors, in USA, are not trained with nutritional avenues of alternate medicine. So it’s Metformin or 2 or 3 others on the prescription market.

Dietary restrictions are one way to help get Hemoglobin A1C levels down. You’re better off consulting a nutritionist. They work with your doctors. Philosophy is different. Doctors approach is what you can’t eat. A nutritionist focuses on what you can eat. How and when.

There’s a good 4-letter word for a diet that literally knocks out all those carbs that drives your pancreas crazy if you’re diabetic 2. The word is Keto. According to keto proponents, by slashing the carbs you consume and instead filling up on fats, you safely enter a state of ketosis. That’s when the body breaks down both dietary and stored body fat into substances called ketones. Your fat-burning system now relies mainly on fat – instead of sugar – for energy.

Proponents claim a keto diet is great for weight loss. Can it reduce diabetes 2 symptoms? The ketogenic diet, according to Healthline, has the potential to decrease blood glucose levels. Managing carbohydrate intake is often recommended for people with type 2 diabetes because carbohydrates turn to sugar and, in large quantities, can cause blood sugar spikes. f you already have high blood glucose, eating too many carbs can be dangerous. By switching the focus to fat, some people experience reduced blood sugar. But fat is also a source of triglyceride. Here again, a nutritionist might be helpful.

One problem with keto are ketones. Diabetic ketoacidosis is a serious complication of diabetes that occurs when your body produces high levels of blood acids called ketones. Theu can be tested with a urine test. When levels get too high, you can develop DKA. DKA may happen to anyone with diabetes, though it is rare in people with type 2. Treatment for DKA usually takes place in the hospital.

Discovering you are pre-diabetic or have diabetes 2 is scary. Is it as scary as doing an hour of cardio-exercise four times a week?

The alternative is to just take Metformin and don’t be frightened until you lose peripheral body parts and lose vision. Yes, that is the long term problems with Diabetes 2.

Your main job is to get your Hemoglobin levels back to safe levels and keep them there. Keep all sugar levels in normal range. Then you’re out of the fear zone. The path is ominous and dark. But you’ve many to co-miserate with. Connect with a diabetes support group and share your experiences. Make friends but don’t go out to dinner. lol

I believe in a holistic attack on diseases. Diabetes 2 is one of them. Diabetes 2 influences your life and your emotions about your life. Change your lifestyle and diet choices. You may soon be clinically diabetes 2 free.

Nurdles are an apocalyptic science fiction but true

Norma sat comfortably but anxious as the Uber drove from the airport to her beachfront community in Siesta Key. She felt warm, though the car seemed to be blasting cool air. She took a issue from her plastic pack of tissues and wiped a tear just beneath her right eye.

It’s been almost a year since Charlie died. She and Charlie were married over 40 years in a coastal town in Maine. When their kids moved, She and C (as she called him) bought the condo off the coast of the Gulf of Mexico. This is the first time Norma snowbirded alone, a little early for the season. She felt she couldn’t bear the cold another year without C.

It’s a long trip from the Tampa airport. She pulled a plastic bag from her carry bag. She tried to get an organic roll. She was frustrated trying to remove its plastic Stay-Fresh package but her stubbornness and hunger aided her.

Norma disliked plastic. But she realized how much plastic was reality. She enjoyed non-stick pans and used plastic utensils. Her phone, tablet, and computer are plastic. Not to mention her travel bags, and some of her clothes. My, plastics were all around!

She and C respected proper disposal of plastic products. Their children were both conservationists, as scientists for studying climate change. “But”, Norma said to herself, “So many people don’t recognize that we need to balance benefits and act responsibly with consequences.” She placed the emptied package into her carry bag.

It was mid-morning as the sun peered through her windows. “From 25 to 80”, she smiled. Norma was dressed and ready for the beach.

“Odd,” she thought as she approached the sandy area. “there’s nobody around”. The sand beneath her feet wasn’t fine and flat. It felt coarse, as if walking on salt. She thought that there might be a maintenance issue. She never reads her e-mail memos.

Time for a short dip. She walked into the water. Although the water was warm, she screamed. When she came ashore, Norma was bleeding and bruised.

Was it a sea creature? A baby shark? A monster from the deep? An alien?

Actually, it was more ominous and dark. It was of this planet and they seemed to be everywhere. They are man-made creatures called Nurdles.

Nurdles are small plastic pellets about the size of a lentil. Countless billion are used each year to make nearly all our plastic products but many end up washing up on our shores. A nurdle is a pre-production plastic pellet.

Plastic resin pellet pollution is a type of marine debris originating from plastic particles utilized in manufacturing large-scale plastics. Commonly referred to as nurdles, these plastics are released into the open environment, creating pollution in the oceans and on beaches. These are manufactured at factories near large bodies of water. In the USA and in other manufacturing countries.

Nurdles the pre-production building blocks for nearly all plastic goods, from soft drink bottles to oil pipelines. Nurdles are bought in bulk for melting, molding, extruding for millions of products used world-wide. Plastics originating as nurdles are in your car, in rails, boats and jets. They may be disguised as metallic or wood. When you touch them, they are plastic.

The Earth Day statisticians state: More than 480 billion plastic bottles were sold worldwide in 2016. That is up from about 300 billion only a decade ago. About one trillion single-use plastic bags are used annually across the globe. That’s nearly 2 million every minute. The amount of bubble wrap used around the world may be wrapped around the equator 10 times. All these and more may owe their origins to nurdles.

Researchers say nurdles weigh an average of approximately 20 milligrams each, and may be found virtually everywhere. It is estimated that more than 250,000 tons enter the ocean annually. If marine life ingest nurdles, they may be endangered. Research shows that nurdles can absorb chemicals like DDT, a now widely banned insecticide; PCBs, a group of manmade industrial chemicals; and mercury.

A report commissioned by Fidra in 2016 estimates that up to 53 billion nurdles may be spilled each year from land-based sources in the UK alone. That’s equivalent to losing up to 88 million plastic bottles to sea over the course of a year.

At the small-end of nurdles infestation is pollution can also lead to significant economic losses, for example through losses in revenue from tourism and the cost of beach cleaning.

So what’s the source of nurdle pollution?

In consideration that nurdles are pre-production synthetic cells that make up most plastic products, pre-production plastic factories are the main source.

A plastic pellet is manufactured. A catalyst is combined with ethylene or propylene in a reactor, resulting in “fluff,” a powdered material (polymer) resembling laundry detergent. After that the polymer is fed to an extruder where it is melted. Melted plastic is cooled then fed to a pelletizer that cuts the product into small pellets. Pellets are shipped to customers. But as a byproduct of manufacturing, pellets make their way to waterways near factories.

Nurdles that become lost during transit or manufacturing are also an environmental hazard. In the ocean and along coastal waterways, they absorb toxic chemicals and are often mistaken for food by animals. At an average size of a 2mm ball these may be mistaken for food.

According to Business Insider, In 2018, thousands of pounds of nurdles wound up in a stream in Pennsylvania after a semi-truck that was carrying them crashed along a highway. The following year, piles of nurdles washed up on Sullivan’s Island beach near Charleston, South Carolina. The state’s Department of Health and Environmental Control later attributed the pollution to a spill from a local shipping company.

Finding actual sources are difficult. There are a few in and near Texas’ gulf coast. Thes pre-production plastic factories provide employment to depressed communities. Generally, pre-production plastic manufacturers have an unaccountable worldwide network.

Much like Earth Day is the annual Global Nurdle Hunt. The Great Global Nurdle Hunt is an annual event (first run in 2019) which aims to build upon the worldwide engagement around the issue of nurdles and support calls for effective mitigating action at industry and government levels. It is scheduled for March 13 – 22 in 2020. The Nurdle Hunt collects data and advocates solutions, albeit mostly focused towards increasing personal responsibility. Nurdle Hint has no legislative authority.

Climate change has some very precarious resources from volcanic vents to nurdle pollution. These will definitely impact the planet in 2050 and prevention requires serious, stern, and authoritative accountability so humans can survive many centuries. At this point, Nurdle Pollution and unacceptability to legislation is as serious as nuclear war.

As far as Norma’s beach incident, she’s fine. Fortunately, the community has a filtered swimming pool. Common charges will increase as staff places netting to prevent further nurdle pollution to accumulate. Sand will be replaced. Yes, new labor for a disconcerting future. Norma is happier.