Diabetes is a pandemic with prevalence in USA and most of the world. Metformin is one of the oral pills prescribe by doctors as an alternative to injected insulin. Metformin is a treatment for Diabetes 2. In order to get cured, a diet and exercise regimen must be integrated as a routine lifestyle. Sadly, most people continue taking pills, drink soda, eat Oreo, and watch TV. Then they wonder why Metformin dose increases as Diabetes grows worse.
More than 100 million U.S. adults are now living with diabetes or prediabetes, according to a recent report released by the Centers for Disease Control and Prevention (CDC). People with type 1 diabetes don’t produce insulin, and are born with it. People with type 2 diabetes don’t respond to insulin as well as they should and later in the disease often don’t make enough insulin, according to Healthline. There have been higher incidences of Diabetes Type 2. Type 2 diabetes has several causes: genetics and lifestyle are the most important ones. A combination of these factors can cause insulin resistance, when your body doesn’t use insulin as well as it should. You may not feel it. Could be major or minor. A blood test at your primary care physician is the best way to get clues.
So you’ve got the results of your blood test. Basic glucose is in normal range. Your triglycerides are in the normal range. But the Hemoglobin A1C is getting mighty close to the pre-diabetic range. The A1c test evaluates the average amount of glucose in the blood over the last 2 to 3 months by measuring the percentage of glycated hemoglobin in the blood and has been added to blood tests over the past 10 years. Now your doctor recommends starting Metformin on prescription. Metformin is a commonly prescribed drug. Metformin works to lower the amount of sugar in the blood of people with diabetes. It does this by lowering the amount of sugar produced in the liver, and also increasing the sensitivity of muscle cells to insulin. In your blood test, it helps reduce your Hemoglobin A1c score. Does it make you non-diabetic?
There are a few things to consider:
Metformin leads to significant reduction in testosterone levels, sex drive and induction of low testosterone-induced erectile dysfunction. Of course so can diabetes.
Commonly reported side effects of metformin include: lactic acidosis, diarrhea, nausea, nausea and vomiting, vomiting, and flatulence. Other side effects include: asthenia, and decreased vitamin B12 serum concentrate. 77% of metformin users with vitamin B12 deficiency also had peripheral neuropathy, a common form of nerve damage associated with type 2 diabetes. Peripheral neuropathy is a type of nerve damage most often characterized by pain, tingling, and numbness in the hands and feet. Vitamin B-12, or cobalamin, is a nutrient you need for good health. It’s one of eight B vitamins that help the body convert the food you eat into glucose, which gives you energy.
Impaired renal function can lead to the accumulation of metformin, and elevated concentrations of metformin have been associated with lactic acidosis.: Metformin may have an adverse effect on renal function in patients with type 2. Metformin is not considered intrinsically hepatotoxic. In fact, metformin may be beneficial in patients with nonalcoholic fatty liver disease. Damaged liver diseases may not work with metformin.
Metformin has been around since the 1920’s. It is based on natural sources. Metformin was originally developed from natural compounds found in the plant Galega officinalis, known as French lilac or goat’s rue. Metformin was also marketed as Glucophage. Generic metformin and Glucophage are prescription medications for Diabetes Type 2, and are taken orally.
We mention that Diabetes 2 may be linked to poor diets and lack of exercise. Medical News Today notes: Exercise can reduce insulin resistance and improve type 2 diabetes symptoms. However, some research suggests that taking metformin in the short term may reduce the positive effects of exercise on insulin sensitivity. One study showed metformin alone and exercise alone led to 55% and 90% improvements in skeletal muscle insulin sensitivity, respectively. Significantly, however, metformin + exercise led to a smaller improvement at 30%.
Is it better to focus on activity lifestyle changes than resorting to Meformin? Does diet factor in?
Per Healthline, Metformin doesn’t really link with helping weight loss. f you’re losing weight while taking metformin, it may or may not be the result of the medication. Weight loss can result from other factors as well. For example, some health conditions may cause loss of appetite, which can lead to weight loss. These conditions include:
chronic obstructive pulmonary disease (COPD)
Classic signs and symptoms that suggest you’ve moved from prediabetes to type 2 diabetes include:
The symptoms of diabetes 2 are something to get depressed and anxious about. The early signs and symptoms of type 2 diabetes can include:
Always feeling hungry.
Feeling very tired.
Slow healing of cuts and wounds.
Tingling, numbness, or pain in the hands or feet.
Patches of dark skin.
According to Mayo Clinic, a blood sugar level less than 140 mg/dL (7.8 mmol/L) is considered normal. A blood sugar level from 140 to 199 mg/dL (7.8 to 11.0 mmol/L) is considered prediabetes. This is sometimes referred to as impaired glucose tolerance. If you receive a prediabetes diagnosis, it means you have a higher-than-normal blood sugar level. But, it’s not high enough to be diagnostic for diabetes. If you don’t get treatment for it, prediabetes can lead to type 2 diabetes, heart disease, and stroke.
Now Hemoglobin A1C makes it simpler. An A1C level below 5.7 percent is considered normal. An A1C level between 5.7 and 6.4 percent is considered prediabetes. Above that, you’ve Diabetes 2 to contend with.
Hypoglycemia is another non-diabetic form of pre-diabetes. Hypoglycemia is the condition when your blood glucose (sugar) levels are too low. It happens to people with diabetes when they have a mismatch of medicine, food, and/or exercise. Non-diabetic hypoglycemia, a rare condition, is low blood glucose in people who do not have diabetes.
Hyperglycemia is the technical term for high blood glucose (blood sugar). High blood sugar happens when the body has too little insulin or when the body can’t use insulin properly.
More doctors and endocrine specialists are happy to prescribe Metformin merely from A1C test results but when you observe the different mechanisms of diabetes a glucose tolerance test should be recommended. A glucose tolerance test measures how well your body’s cells are able to absorb glucose (sugar) after you consume a specific amount of sugar. Doctors use fasting blood sugar levels and hemoglobin A1c values to diagnose type 1 and type 2 diabetes as well as prediabetes. These tests may last 1 to 3 hours on average.
According to Healthline, a two-hour, 75-gram oral glucose tolerance test (OGTT) is used to test for diabetes. A healthcare provider will take a fasting lab draw of blood to test your fasting glucose level first. They’ll then ask you to drink 8 ounces of a syrupy glucose solution that contains 75 grams of sugar.
You’ll then wait in the office for two hours. The healthcare provider will draw blood at the one- and two-hour marks.
Blood glucose, or sugar, is sugar that is in your blood (easy enough!). It comes from the food that you eat — foods that contain carbohydrate, such as bread, pasta and fruit are the main contributors to blood glucose. The cells in our bodies need glucose for energy — and we all need energy to move, think, learn and breathe. The brain, which is the command center, uses about half of all the energy from glucose in the body. When we eat food, the pancreas (an organ that sits between the stomach and the spine) goes to work, releasing enzymes that help to break down food and hormones that help the body handle the influx of glucose. One of these hormones is insulin, and it plays a key role in managing glucose levels in the blood.
The lifestyle changes are exercises and reducing carbohydrate consumption throughput the day.
There are supplements that may be good alternatives to Metformin use:
Chromium is an essential trace mineral that helps the hormone insulin to function at its full potential. Nicotinate and picolinate are two forms of chromium. … Additionally, in a direct comparison against chromium nicotinate, the picolinate source was less effective in supporting the action of insulin.
Cinnamon may help lower blood sugar and fight diabetes by imitating the effects of insulin and increasing glucose transport into cells ( 6 ). It can also help lower blood sugar by increasing insulin sensitivity, making insulin more efficient at moving glucose into cells.
Vanadium compounds are potent in controlling elevated blood glucose levels in experimentally induced diabetes. However the toxicity associated with vanadium limits its role as therapeutic agent for diabetic treatment.
Bitter melon is linked to lowering the body’s blood sugar. This is because the bitter melon has properties that act like insulin, which helps bring glucose into the cells for energy.
Of course neither of these supplements haven’t received FDA approval to support or deny their claims. Most evidence is derived from small studies in Europe and Asia.
Sunergetic Blood Sugar Support has all the above and more. It helps me keep my A1C scores within normal range. But this claim is by no means scientific.
Large overdoses of metformin can lead to lactic acidosis as well. Suicide with metformin is rare. Intake of 35 g of metformin has been shown to be lethal. Severe liver problems could lead to a buildup of lactic acid. Lactic acid buildup raises your risk of lactic acidosis. Metformin also raises your risk, so taking it if you have liver problems is dangerous.
Because supplements have little supporting research, no figures were established. Properly dosing supplements requires a good licensed nutritionist. It will help recommend dosage to avoid side effects. Doctors, in USA, are not trained with nutritional avenues of alternate medicine. So it’s Metformin or 2 or 3 others on the prescription market.
Dietary restrictions are one way to help get Hemoglobin A1C levels down. You’re better off consulting a nutritionist. They work with your doctors. Philosophy is different. Doctors approach is what you can’t eat. A nutritionist focuses on what you can eat. How and when.
There’s a good 4-letter word for a diet that literally knocks out all those carbs that drives your pancreas crazy if you’re diabetic 2. The word is Keto. According to keto proponents, by slashing the carbs you consume and instead filling up on fats, you safely enter a state of ketosis. That’s when the body breaks down both dietary and stored body fat into substances called ketones. Your fat-burning system now relies mainly on fat – instead of sugar – for energy.
Proponents claim a keto diet is great for weight loss. Can it reduce diabetes 2 symptoms? The ketogenic diet, according to Healthline, has the potential to decrease blood glucose levels. Managing carbohydrate intake is often recommended for people with type 2 diabetes because carbohydrates turn to sugar and, in large quantities, can cause blood sugar spikes. f you already have high blood glucose, eating too many carbs can be dangerous. By switching the focus to fat, some people experience reduced blood sugar. But fat is also a source of triglyceride. Here again, a nutritionist might be helpful.
One problem with keto are ketones. Diabetic ketoacidosis is a serious complication of diabetes that occurs when your body produces high levels of blood acids called ketones. Theu can be tested with a urine test. When levels get too high, you can develop DKA. DKA may happen to anyone with diabetes, though it is rare in people with type 2. Treatment for DKA usually takes place in the hospital.
Discovering you are pre-diabetic or have diabetes 2 is scary. Is it as scary as doing an hour of cardio-exercise four times a week?
The alternative is to just take Metformin and don’t be frightened until you lose peripheral body parts and lose vision. Yes, that is the long term problems with Diabetes 2.
Your main job is to get your Hemoglobin levels back to safe levels and keep them there. Keep all sugar levels in normal range. Then you’re out of the fear zone. The path is ominous and dark. But you’ve many to co-miserate with. Connect with a diabetes support group and share your experiences. Make friends but don’t go out to dinner. lol
I believe in a holistic attack on diseases. Diabetes 2 is one of them. Diabetes 2 influences your life and your emotions about your life. Change your lifestyle and diet choices. You may soon be clinically diabetes 2 free.